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This is a guide for an introductory analysis to 1) construct a polygenic risk score (PRS) using the base data (GWAS summary statistics, particularly with effect-sizes and P-values, generally public publicly available) via a clumping and thresholding method (C + T); and 2) test the constructed PRS for prediction using the target data (PLINK binary data formatfiles and phenotype csv file). In general, it is the ‘user’ data).
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