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Krembil Centre for Neuroinformatics Summer School

Solving Problems in Mental Health using Multi-Scale Computational Neuroscience

Distribution Date: June 2022

Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health



Join us for the Krembil Centre For Neuroinformatics Open House!



Introductory Concepts (July 5, 2021)


Topic
InstructorVideoSlides

A Multiscale Approach to Brain Disorders

Sean Hill, Ph.D. Director, Krembil Centre for Neuroinformatics Senior Scientist, Centre for Addiction and Mental Health Professor, Departments of Psychiatry and Physiology, University of Toronto, Canada Titular Professor, École Polytechnique Fédérale de Lausanne, Switzerland krembilneuroinformatics.ca

Watch on Crowdcast
slides

Problems and opportunities in the diagnosis and treatment of major depression

Victor Tang MD MSc, Clinician-Scientist/Resident,Centre for Addiction and Mental Health, Twitter: @victormarktang

Brett Jones MD MSc, Clinician-Scientist/Resident, Centre for Addiction and Mental Health

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slides


Computing Fundamentals

For those who need more help with computing fundamentals - going into the later content. We recommend content available from the KCNI Scientific Computing Working Group.

TopicTutorial VideosOnline TutorialsPrerequisit to
R


Python

Those working with imaging data
Git/Github


Linux/Bash




Reproducible Science (including Docker and Binder) 

2022 Watch Party Time (EST)
Session
InstructorsVideoMaterials

Workshop 1: Guiding principles for FAIR and open science
Erin Dickie, Sejal Patel
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slides

Workshop 2: Tools for Reproducible Science
Erin Dickie, Sejal Patel
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github code

rstudio example Binder jupyter example Binder



Applied Ethics in Machine Learning and Mental Health 

2022 Watch Party Time
Topic
InstructorVideoMaterials

Lecture 1: Introduction to AI Ethics
Daniel Buchman
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Lecture 2:  Fairness and Health Equity
Marta Maslej & Laura Sikstrom
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Workshop 1: Research Design, Data Collection, Model Construction and Validation
Marta Maslej & Laura Sikstrom
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Workshop 2: Analysis, Interpretation and Knowledge Exchange and/or Translation
Marta Maslej & Laura Sikstrom
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All videos previously recorded July 6th, 2021 as part of the KCNI Summer School



Digital Health

Time (EST)
Session
InstrutorVideoMaterials

Lecture 1: Digital Health for Mental health

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Workshop 1: accessing reproducible datasets from Synapse as part of integrated workflow

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Fundamental Methods for Genomic Analysis

Time (EST)
Session
InstructorVideoMaterials

Lecture 1: Basics of genotype, central dogma, GWAS, and polygenic risk scores
Dan Felsky
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Workshop 1: Intro to transcriptomic data types, including single-cell and bulk RNAseq
Dan Felsky
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All videos previously recorded July 7th, 2021 as part of the KCNI Summer School



Fundamental Methods for Single-Cell Transcriptome Analysis


Session
InstructorVideoMaterials

Lecture 1:  Transcriptomics at the single-cell and bulk level level
Shreejoy Tripathy
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Workshop 1: Intro to transcriptomic data types, including single-cell and bulk RNAseq
Dan Felsky
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Workshop 2: Explore cellular changes in major depression using bulk and single-cell RNAseq data
Dan Felsky
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All videos previously recorded July 7th, 2021 as part of the KCNI Summer School

TA's:  Keon Arbabi, Sonny Chen, Micaela Consens, Amin Kharaghani


Simulating Brain Microcircuit Activity and Signals in Mental Health

Watch Party Time (EST)
Session
InstructorsVideoMaterials

Lecture 1: Simulating brain microcircuit activity in mental health

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Lecture 2: Simulating EEG from brain microcircuits in mental health

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Workshop 1: Simulating and analyzing spiking from neurons and microcircuits

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Workshop 2: Simulating and analyzing EEG signals from brain microcircuits

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All videos previously recorded July 8th, 2021 as part of the KCNI Summer School



Neuroimaging Connectomics

Time (EST)
Session
InstructorsVideoMaterials

Lecture 1: Introduction to neuroimaging connectomics
Erin Dickie & John Griffiths
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Workshop 1: Calculating Neuroimaging Connectomes
Erin Dickie & John Griffiths
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All videos previously recorded July 9th, 2021 as part of the KCNI Summer School




Whole-Brain Modelling

Time (EST)
Session
InstructorsVideoMaterials

Lecture 2: Intro to whole-brain modelling (Lecture)
John Griffiths
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Workshop 2: simulating whole-brain activity, EEG, evoked responses, brain stimulation
John Griffiths
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All videos previously recorded July 9th, 2021 as part of the KCNI Summer School



Bayesian Models of Learning and Integration of Neuroimaging Data

Time (EST)
Session
InstructorVideoMaterials

Lecture 1: Bayesian Models of Learning

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Turorial 1:  Hierarchical Gaussian Filter and Simulating Learners

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Lecture 2: Computational Modelling of EEG Data

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Tutorial 2: Single-trial EEG Modelling

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All videos previously recorded July 12th, 2021 as part of the KCNI Summer School
TA's: Colleen Charlton, Daniel Hauke, Peter Bedford, Povilas Karvelis




Population-Based Data Resources & Integrative Research Methods


Session
InstructorVideoMaterials

Lecture 1: Population-based resources and the BrainHealth Databank
Joanna Yu



Workshop 1: Introduction to interactive methods
Daniel Felsky



Lecture 2: Types of integrative research and Whole Person Modelling
Daniel Felsky
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Workshop 2: SNF / Subtyping
Daniel Felsky
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2020 Summer School Overview




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