Suggestions and Feedback? Email us at krembil.centre@camh.ca
The Krembil Centre for Neuroinformatics at CAMH || Looking for more? Email us at krembil.centre@camh.ca
This Month:
DATE:
EVENT DETAILS / TOPIC:
SPEAKER(S):
Wednesday, November 4, 2020 at 9:30 to 12:30pm
Fairness and Equity Workshop: The proposed workshop will explore the ways that bias “gets baked into” our data and models at five different stages of the research cycle: 1) Research Design; 2) Data Collection; 3). Data Editing and Analysis; 4) Model Construction and Validation; 5) Knowledge Translation and Exchange.
Key objectives of this workshop are to identify potential sources of bias in our own research, and promote best practices in the field and among our peers.
Register here
Dr. Laura Sikstrom is a CIHR Health System Impact Fellow and Lecturer in the Department of Anthropology at the University of Toronto. Her ongoing teaching and research engages with the intersection between evidence based medicine, health equity and social justice. Her current project is an institutional ethnography of fairness at CAMH.
Wednesday, November 4, 2020 at 3 to 3:40pm
Dr. Sean Hill, Director of the Krembil Centre for Neuroinformatics will deliver a talk on transforming mental health care through new approaches to gathering data inside and outside the clinic, providing next generation AI decision support to clinicians, and constructing multi-scale computational models that integrate genomics, cells and circuits, whole brain dynamics, cognitive networks and whole person level data.
Friday, November 20, 2020 at 10 to 12pm
STATISTICAL METHODS FOR GENETICS & GENOMICS - RESEARCH SEMINAR AND JOURNAL CLUB
TOPIC: Linking central and peripheral inflammation in Alzheimer’s disease using genetics and transcriptomics
Abstract: Neurodegeneration due to Alzheimer’s disease is the most common cause of major cognitive impairment in late life and is characterized by the presence of amyloid plaques, neurofibrillary tangles, and chronic inflammation in the brain. The brain’s resident immune cells, microglia, mediate the destructive series of events leading to neuron loss. However, these cells are inaccessible in living humans. Peripheral blood monocytes, on the other hand, bear morphological and functional similarity to microglia and are directly testable. A series of published and unpublished results seeking to clarify the roles of microglia and monocytes in Alzheimer’s disease will be presented, showcasing approaches to studying the integrative multi-‘omic, ante- and post-mortem datasets collected on participants from the Rush University Religious Orders Study and Memory and Aging Project.
Readings:
1. Felsky et al (2019) https://www.nature.com/articles/s41467-018-08279-3
2. Bennett et al (2018) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380522/
https://content-iospress-com.myaccess.library.utoronto.ca/articles/journal-of-alzheimers-disease/jad179939?resultNumber=0&totalResults=448&start=0&q=Bennett&resultsPageSize=10&rows=10
Zoom link
Meeting ID: 845 1361 2646
Passcode: 824465
Dr. Daniel Felsky is an Independent Scientist and Head of Whole Person Modeling in the Krembil Centre for Neuroinformatics at CAMH. He is also an Assistant Professor in the Department of Psychiatry at the University of Toronto.
Dr. Felsky completed his PhD in neuroimaging and genetics of Alzheimer’s disease at CAMH in 2015. Following this, Dr. Felsky completed postdoctoral fellowships at the Anne Romney Center for Neurologic Diseases at Brigham and Women’s Hospital, Harvard Medical School, in Boston, and the Centre for Translational and Computational Neuroimmunology at Columbia University Medical Centre in New York. As a postdoctoral fellow, Dr. Felsky studied the genetic links between central and peripheral immune diseases and the morphology of the brain’s resident immune cells, microglia. While in Boston and New York, Dr. Felsky collaborated closely with investigators at Rush University Medical Centre in Chicago, publishing the first genome-wide study of microglial activation in humans.
Thursday, November 26, 2020 at 6:30 to 7:30pm
OBI Public Talk - Brain-CODE/Data Sharing
Twitter: https://bit.ly/3emWCLh
LinkedIn: https://bit.ly/3eqtsv4
Facebook: https://bit.ly/3kTj1Tb
Register here
Dr. Sean Hill, Director of the Krembil Centre for Neuroinformatics will deliver a talk on transforming mental health care through new approaches to gathering data inside and outside the clinic, providing next generation AI decision support to clinicians, and constructing multi-scale computational models that integrate genomics, cells and circuits, whole brain dynamics, cognitive networks and whole person level data.
Upcoming:
Wednesday, December 2 to 4, 2020
BrainHack Global 2020: Ontario
A virtual event co-hosted by BrainHack Western and BrainHack Toronto
Registration is now opened for our first virtual BrainHack Global - Ontario co-hosted by BrainHack Western and BrainHack Toronto. Join us on December 2nd to 4th over Chrowdcast for a completely free event focused on neuroscience and the promotion of open-source resources in an accessible way across disciplines and experience levels including hacking, education, panels, and networking.
For more information, please visit the BrainHack site (https://brainhackto.github.io/global-ON-2020/), which will be updated regularly. If you have any questions, please feel free to contact us brainhacktoronto@gmail.com or brainhack.western@gmail.com
Register here
BrainHacks are collaborative events that focus on the open sharing of ideas, models, code, and data. We will be featuring speakers, panels, and tutorials. Attendees will have the opportunity to work with others to pitch ideas, create projects, and share their achievements with others.
Even though we will be physically distant, there will be the possibility to come together and socialize on the Brainhack Ontario GatherTown platform. We will be using the platform to host exciting social activities throughout the event. Stay tuned for the social activities program!
We invite all neuroscience aficionados, students of neuroscience-related subjects, professors and professionals to participate. Registrations are now open here.
Thursday, December 10, 2020 at 4 to 5pm
University of Toronto Seminar Series for Physiology
Event details: TBC.
Dr. Sean Hill, Director of the Krembil Centre for Neuroinformatics will deliver a talk on transforming mental health care through new approaches to gathering data inside and outside the clinic, providing next generation AI decision support to clinicians, and constructing multi-scale computational models that integrate genomics, cells and circuits, whole brain dynamics, cognitive networks and whole person level data.
Thursday, December 10, 2020 at 10 to 11:30am
KCNhub Event
TOPIC: Hierarchical Bayesian inference underpins human social learning
Zoom link
Meeting ID: 896 8176 7784
Passcode: 593617
Dr Andreea Diaconescu is an Independent Scientist at the Krembil Centre for Neuroinformatics (CAMH) and Assistant Professor in the Department of Psychiatry at the University of Toronto.
Andreea completed her PhD in Cognitive Neuroscience with Prof. Randy McIntosh at the Rotman Research Institute (University of Toronto). Following her PhD training, she held a postdoctoral position at the Translational Neuromodeling Unit (University of Zurich and ETH Zurich). Under the supervision of Prof. Klaas Enno Stephan, she developed, validated, and applied hierarchical Bayesian models of social learning and decision-making to examine persecutory ideation in early psychosis. Andreea has recently been supported by the Swiss National Foundation at the University in Basel in the Department of Psychiatry to lead a project on early detection of psychosis using computational models of persecutory delusions fit to behaviour and neuroimaging (EEG and fMRI) data.
At the Krembil Centre for Neuroinformatics, Andreea focuses on neurocomputational models of suicidal ideation in psychoaffective disorders.
Tuesday, December 15, 2020 at 12 to 1pm
CAMH Trainee Seminar Series: The CAMH research trainee seminars are back! This seminar series is an opportunity to learn about the work of research trainees across CAMH. Talks will resume on Sept. 8, and be held every second Tuesday from 12-1 pm.
Topic: MRI-based subtyping of depression in the UK Biobank
Zoom link
Dr. Michael Wainberg, post-doc of Dr. Shreejoy Tripathy
Thursday, January 28, 2021 at 11 to 12pm
Tübingen Neuro Campus (TNC) Virtual talk
Event details: Zoom TBC
Dr. Sean Hill, Director of the Krembil Centre for Neuroinformatics will deliver a talk on transforming mental health care through new approaches to gathering data inside and outside the clinic, providing next generation AI decision support to clinicians, and constructing multi-scale computational models that integrate genomics, cells and circuits, whole brain dynamics, cognitive networks and whole person level data.
Past:
Tuesday, October 20, 2020 at 12 to 1pm
CAMH Trainee Seminar Series: This CAMH seminar series is an opportunity to learn about the work of research trainees across CAMH. Talks will resume on Sept. 8, and be held every second Tuesday from 12-1 pm.
Topic: Predicting post-treatment MDD symptom severity based on topic modelling features from psychiatric notes
Zoom link
Dr. Marta Maslej, post-doctoral fellow of Dr. Sean Hill
Wednesday, October 21, 2020 at 9 to 10am
Adeel Ansari, Knowledge Engineering Lead
Wednesday, October 28, 2020 at 9:30 to 12:30pm
Fairness and Equity Workshop: The proposed workshop will explore the ways that bias “gets baked into” our data and models at five different stages of the research cycle: 1) Research Design; 2) Data Collection; 3). Data Editing and Analysis; 4) Model Construction and Validation; 5) Knowledge Translation and Exchange.
Key objectives of this workshop are to identify potential sources of bias in our own research, and promote best practices in the field and among our peers.
This workshop is FULL - Sign up for Nov 4!
Dr. Laura Sikstrom is a CIHR Health System Impact Fellow and Lecturer in the Department of Anthropology at the University of Toronto. Her ongoing teaching and research engages with the intersection between evidence based medicine, health equity and social justice. Her current project is an institutional ethnography of fairness at CAMH.
Wednesday, October 28, 2020 at10 to 11:30am
Marcos Sanches, Biostatistician