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Krembil Centre for Neuroinformatics Summer School

Solving Problems in Mental Health using Multi-Scale Computational Neuroscience

Distribution Date: June 2022

Krembil Centre for Neuroinformatics, Centre for Addiction and Mental Health


KCNI Open House 2022_Poster.png

Join us for the Krembil Centre For Neuroinformatics Open House!

Krembil Centre for Neuroinformatics Virtual Open House

The Krembil Centre for Neuroinformatics is excited to host its Annual Open House on Friday, June 24 starting at 10am.

Come meet the KCNI team and learn about the latest developments virtually, or even better, in person!

Register for in-person or virtual here.


Introductory Concepts

A collection of lectures on overaching concepts in Neuroinformatics Research.


Topic
InstructorVideoSlides

A Multiscale Approach to Brain Disorders

Sean Hill, Ph.D. Director, Krembil Centre for Neuroinformatics Senior Scientist, Centre for Addiction and Mental Health Professor, Departments of Psychiatry and Physiology, University of Toronto, Canada Titular Professor, École Polytechnique Fédérale de Lausanne, Switzerland krembilneuroinformatics.ca

Watch on Crowdcast
slides

Problems and opportunities in the diagnosis and treatment of major depression

Victor Tang MD MSc, Clinician-Scientist/Resident,Centre for Addiction and Mental Health, Twitter: @victormarktang

Brett Jones MD MSc, Clinician-Scientist/Resident, Centre for Addiction and Mental Health

Watch on Crowdcast
slides

Computing Fundamentals

For those who need more help with computing fundamentals - going into the later content. We recommend content available from the KCNI Scientific Computing Working Group.

TopicTutorial VideosOnline TutorialsPrerequisit to
R(see recording within tutorials page)R Workshop Material (Apr-Jun 2022)


Python
Introduction to PythonThose working with imaging data
Git/Github
Introduction to Git and GitLab
Linux/BashYoutubeIntroduction to Linux and Bash

many recordings available via from last falls series. SCWG Workshop Recordings - Nov 2021 Series


 

Register for Virtual Q&A  - June 10, 2022 1:00pm EST

Reproducible Science (including Git, Docker and Binder) 

Register for Virtual Q&A  - June 10, 2022 1:00pm EST

2022 Watch Party Time
  (EST)
Session
InstructorsVideoMaterials
9:30-11:00am
Workshop 1: Guiding principles for FAIR and open science
Erin Dickie, Sejal Patel
Watch on Crowdcast
slides
11:00-12:30pm
Workshop 2: Tools for Reproducible Science
Erin Dickie, Sejal Patel
Watch on Crowdcast

github code

rstudio example Binder jupyter example Binder


Register for the Virtual Q&A

3:30pm EST

Applied Ethics in Machine Learning and Mental Health 

Register for the Virtual Q&A 3:30pm EST

2022 Watch Party Time

EST

Topic
InstructorVideoMaterials
9:00-10:30am
Lecture 1: Introduction to AI Ethics
Daniel Buchman
Watch on Crowdcast

10:30-12:00pm
Lecture 2:  Fairness and Health Equity
Marta Maslej & Laura Sikstrom
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slides
12:30-2:00pm
Workshop 1: Research Design, Data Collection, Model Construction and Validation
Marta Maslej & Laura Sikstrom
Watch on Crowdcast
2:00-3:30pm
Workshop 2: Analysis, Interpretation and Knowledge Exchange and/or Translation
Marta Maslej & Laura Sikstrom
Watch on Crowdcast

All videos previously recorded July 6th, 2021 as part of the KCNI Summer School


Digital Health for Mental Health

Presented by Abhi Pratap

Register for Virtual Q&A  - June 20, 2022 1:00pm EST

Watch Party  
Time (EST)
Session
InstructorVideoMaterials
9:30-11:00am
Lecture 1: Digital Health for Mental health
Abhi Pratap
Watch on Crowdcast

11:00-12:30pm
Workshop 1: accessing reproducible datasets from Synapse as part of integrated workflow
Abhi Pratap
Watch on Crowdcast
All videos previously recorded July 13th, 2021 as part of the KCNI Summer School


The workshop demostates how to work with the Synapse platform.

Workshop 1 will use push and pull data to the synapse platform for sharing biomedical datasets using the synapseClient python package. In order to be able to run all the commands in tutorial 1, a "verified" synapse account is required. For folks who are not able to create an account or get certified before the session tomorrow the instructor will cover the concepts for tractable data analysis that can still be generally applicable beyond synapse platform. Getting a Verified Account is a two step process.


Fundamental Methods for Genomic Analysis

Time (EST)
Session
InstructorVideoMaterials

Lecture 1: Basics of genotype, central dogma, GWAS, and polygenic risk scores
Dan Felsky
Watch on Crowdcast


Dan Felsky
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code (GitHub)

Workshop 2: Calculation of polygenic risk scores in PRSiceDan FelskyWatch on Crowdcastcode (GitHub)

All videos previously recorded July 7th, 2021 as part of the KCNI Summer School


Fundamental Methods for Single-Cell Transcriptome Analysis


Session
InstructorVideoMaterials

Lecture 1:  Transcriptomics at the single-cell and bulk level level
Shreejoy Tripathy
Watch on Crowdcast
slides

Workshop 1: Intro to transcriptomic data types, including single-cell and bulk RNAseq
Dan Felsky
Watch on Crowdcast

Workshop 2: Explore cellular changes in major depression using bulk and single-cell RNAseq data
Dan Felsky
Watch on Crowdcast

All videos previously recorded July 7th, 2021 as part of the KCNI Summer School

TA's:  Keon Arbabi, Sonny Chen, Micaela Consens, Amin Kharaghani

Simulating Brain Microcircuit Activity and Signals in Mental Health

Watch Party Time (EST)
Session
InstructorsVideoMaterials

Lecture 1: Simulating brain microcircuit activity in mental health
Etay Hay & Frank Mazza
Watch on Crowdcast
slides

Lecture 2: Simulating EEG from brain microcircuits in mental health
Etay Hay & Frank Mazza
Watch on Crowdcast
slides

Workshop 1: Simulating and analyzing spiking from neurons and microcircuits
Etay Hay & Frank Mazza
Watch on Crowdcast

Workshop 2: Simulating and analyzing EEG signals from brain microcircuits
Etay Hay & Frank Mazza
Watch on Crowdcast

All videos previously recorded July 8th, 2021 as part of the KCNI Summer School


Neuroimaging Connectomics

Time (EST)
Session
InstructorsVideoMaterials

Lecture 1: Introduction to neuroimaging connectomics
Erin Dickie & John Griffiths
Watch on Crowdcast
slides

Workshop 1: Calculating Neuroimaging Connectomes
Erin Dickie & John Griffiths
Watch on Crowdcast
All videos previously recorded July 9th, 2021 as part of the KCNI Summer School



Whole-Brain Modelling

Time (EST)
Session
InstructorsVideoMaterials

Lecture 2: Intro to whole-brain modelling (Lecture)
John Griffiths
Watch on Crowdcast


Workshop 2: simulating whole-brain activity, EEG, evoked responses, brain stimulation
John Griffiths
Watch on Crowdcast

All videos previously recorded July 9th, 2021 as part of the KCNI Summer School


Bayesian Models of Learning and Integration of Neuroimaging Data

Coding Language: MATLAB more setup info


Time (EST)
Session
InstructorVideoMaterials

Lecture 1: Bayesian Models of Learning
Andreea Diaconescu
Watch on Crowdcast
slides

Turorial 1:  Hierarchical Gaussian Filter and Simulating Learners
Andreea Diaconescu
Watch on Crowdcast
code (github)

Lecture 2: Computational Modelling of EEG Data
Andreea Diaconescu
Watch on Crowdcast
slides

Tutorial 2: Single-trial EEG Modelling
Andreea Diaconescu
Watch on Crowdcast
code (github)
All videos previously recorded July 12th, 2021 as part of the KCNI Summer School
TA's: Colleen Charlton, Daniel Hauke, Peter Bedford, Povilas Karvelis



Population-Based Data Resources & Integrative Research Methods


Session
InstructorVideoMaterials

Lecture 1: Population-based resources and the BrainHealth Databank
Joanna Yu
Watch on Crowdcastslides

Workshop 1: Introduction to interactive methods
Daniel Felsky
Watch on Crowdcast

Lecture 2: Types of integrative research and Whole Person Modelling
Daniel Felsky
Watch on Crowdcast


Workshop 2: SNF / Subtyping
Daniel Felsky
Watch on Crowdcast

2020 Summer School Overview




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